Aripiprazole is effective in reducing mania in bipolar disorder, tics in Tourette Syndrome, aggression in schizophrenia and spectrum autism disorder. Moreover, it is a partial agonist of the dopamine D2 receptor (D2 receptor) and serotonin (5-HT) 1A (5-HT1A) receptor and also binds to adrenergic α1, histaminic H1 and muscarinic receptors. Our findings lead us to suggest that aripiprazole is less burdened with side effects, including bedwetting, than other antipsychotic drugs.Īripiprazole is a third-generation atypical antipsychotic drug that stabilizes the dopaminergic and serotonergic systems. ![]() ![]() The aim of this study was to contribute to the literature on the use of aripripazole in subjects with enuresis. We report the disappearance of enuresis in a Caucasian girl with intellectual disability and oppositional defiant disorder and in a Caucasian boy with intellectual disability and early-onset psychosis, both following initiation of treatment with aripiprazole. Only a few studies, with conflicting results, have investigated the relationship between aripiprazole and enuresis. Enuresis has been reported among its side effects. As partial agonist of the dopamine (D2) and serotonin (5-HT1A) receptors, it appears to be effective in reducing mania in patients with bipolar disorder, tics in Tourette Syndrome, aggression in schizophrenia and autism spectrum disorder. All rights reserved.Aripiprazole is a third-generation atypical antipsychotic drug that acts as a stabilizer of the dopaminergic and serotonergic system. Parasomnia Questionnaire Sleep disordered breathing Sleep disturbance scale for children Sleep enuresis.Ĭopyright © 2015 European Paediatric Neurology Society. The novel finding of this study is that we found a decreased incidence of DIMS that is consistent with the parental perception of a more deep sleep and a high arousal threshold in SE. No differences were found for the DOES and SHY subscales.Įnuretic children showed a high comorbidity with other sleep disturbances like sleep disordered breathing and parasomnias. Children with renal and neurological problems were excluded from both groups.Įnuretics scored higher in several of the subscales (SBD, DOA, SWTD) and also in the total scale scores while scored low in the DIMS subscale. The Scale is grouped into six subscales: Disorders in Initiating and Maintaining Sleep (DIMS), Sleep Breathing Disorders (SBD), Disorders of Arousal (DA), Sleep-Wake Transition Disorders (SWTD), Disorders Of Excessive Somnolence (DOES), and Nocturnal Hyperhidrosis (SHY). The aim of this study was to analyze the presence of sleep disturbances in children with SE through the use of Sleep Disturbance Scale for Children (SDSC) compared to normal children matched for age and sex.Ī questionnaire evaluation was performed in 76 enuretic and 112 normal children through the Sleep Disturbance Scale for Children (SDSC) validated for Portuguese language. ![]() Several sleep disorders have been described in association with SE like parasomnias and sleep apnea. It has been associated with bladder hyperactivity, excessive urine production and deeper sleep. Sleep enuresis (SE) is the second most common sleep complaint in childhood.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |